Managing MRONJ: Bisphosphonates and Denosumab in Dental Practice

Treating dental patients who take antiresorptive medications requires precise risk evaluation to prevent severe complications like Medication-Related Osteonecrosis of the Jaw (MRONJ). This comprehensive written guide provides clinicians with clear frameworks to evaluate patient histories, plan safe dental procedures, and manage osteonecrosis effectively. You will build a thorough understanding of how antiresorptive and antiangiogenic medications impact bone remodeling and how to tailor dental interventions around patient medical histories. What you'll learn: - Understand the pharmacological mechanisms and clinical indications of bisphosphonates and denosumab - Identify systemic and local risk factors contributing to medication-related osteonecrosis - Apply evidence-based preventive protocols prior to invasive dental treatments and extractions - Recognize clinical diagnostic signs, staging criteria, and imaging findings of MRONJ - Implement non-surgical and surgical management strategies based on disease stage - Coordinate interdisciplinary communication with prescribing physicians and oncologists The course begins with foundational terminology, bone biology, and pharmacology principles before advancing to detailed clinical workflows, staging guidelines, and practical case management strategies. This course is ideal for general dentists, dental specialists, hygienists, and dental students seeking to establish safe clinical practices for medically compromised patients. No specialized prior knowledge in advanced oral surgery is required. Start reading today to deliver safer and more confident care for patients on antiresorptive therapy.